Good question Michael...
I think my answer is more for the person that is looking to generate a consistent 6-figure income year after year using a reliable system.
I personally like a system where:
1. You offer a product that is already being searched for on Google.
2. You either go head-to-head with existing vendors and attempt to beat them based upon...
A. Better marketing/sales copy.
B. A lower price to the end-user.
C. Faster delivery.
D. Additional "bonuses" given.
OR
You offer a slightly "better" product at either the same or less money.
Heck you could actually employ both strategies at once via two separate sites.
3. Use a fulfillment company to process and ship the orders.
What kind of product should you consider offering?
My gosh with the ability to have just about any product under the sun made, improved upon or just "knocked off" let your imagination run wild!
Is this business model going to cost you some up front money in order to get it going? You bet. But if you played your cards right I'm sure it would cost less than $10,000 to start.
And if you don't have that sort of scratch to get it going use one of the other methods listed at the start of this thread. That's what I did, I sold info products mostly via ebay until I built up enough of an "investment war chest" which allowed me to take my business to the "next level".
But the fact is this type of business model can be used just about anywhere in the world that has Internet access.
Here's a real life example of how one business is using the net to access customers in a way that you would not have thought was feasible...
In my business I go thought a ton of address labels and for the last 2 years I've been getting them from this one website that offers reasonably fast service and decent prices...
http://www.addresslabels4u.com/
Well come to find out they're located in the U.K. and they've done a wonderful job of selling to customers within the U.S. and Canada. Heck by looking at the site you wouldn't know they were based in the U.K. They have done a wonderful job at eliminating "borders", "oceans" and entire countries from the buying decision.